Scientist (Next Generation Sequencing)
We are seeking a motivated, creative, and experienced Molecular Biologist to join a highly collaborative team focused on revolutionizing precision, and personalized patient care using cutting-edge technologies. The candidate will have molecular biology and microbiology expertise including next generation sequencing, library preparation, nucleic acid extraction, as well as experience working with infectious disease samples. The candidate will also process patient samples for transcript analysis, imaging, and other bioanalytical platforms. Role Requirements:
- PhD in molecular biology, biology, chemistry, biochemistry, genetics, or related field
- 5+ years of experience in molecular biology techniques including performing high quality nucleic acid (especially RNA) extraction from fresh/frozen tissue, FFPE, blood or other body fluids, next generation sequencing, library preparation, QC analysis for nucleic acid integrity and purity, PCR, and high throughput transcript analysis
- Provides subject matter expertise in development and implementation of molecular assays
- Proficient in mammalian cell culture, circulating tumor cells, proliferation/apoptosis assays, design of experiments including control experiments
- Expert in standard laboratory procedures, molecular biology techniques, documentation, and data analysis
- Experience in preparation of slides for imaging and image analysis
- Ability to troubleshoot, modify, and adapt to new workflows as required for analysis
- Identify and learn new techniques as well as multi-task
- Operate, maintain, and troubleshoot lab equipment
- Excellent collaboration, interpersonal, and problem-solving skills
- Knowledgeable about good laboratory practices and biosafety protocols
- Develop, validate, and execute workflows for nucleic acid and imaging analysis
- Isolate and identify cancer cells using molecular and imaging techniques
- Perform library preparation and NGS
- Extract and purify high quality nucleic acids as well as perform quality control analysis for assessing nucleic acid integrity and purity
- Proactively employ a range of cellular and molecular biology techniques
- Prepare patient samples for analysis using a range of techniques including imaging
- Design and execute experiments, analyze, and interpret the results
- Analyze high throughput data, generate reports, and integrate into LIMS platform
- Collect, prepare and manage SOPs
- Manage the use of laboratory reagents and supplies
- Contribute to scientific publications as needed
- Perform other duties as assigned
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